Natalie, known as Natsumi in Japan and the European dub of Ape Escape 2 and Ape Escape 3 and Ape Escape: On The Loose (ナツミ), and Katie in the original European dub of Ape Escape, is the Professor's granddaughter and first female character in the series. She helps keep the lab in a good shape and makes sure that the monkeys are caught. She is the inventor of the new Monkey Helmet that can let Spike and his friends control monkeys by placing it on the regular Pipo Helmet.
Natalie wears a blue dress in the first Ape Escape game and its PSP remake.
In Ape Escape 2, she wears a sleeveless blue shirt with a yellow shirt under it, with blue jeans and red sandals.
She wears the same clothes in Ape Escape 3, though now the sleeveless shirt is green.
In Ape: Escape: Pumped & Primed, she has a new outfit. She now wears a white shirt, blue jeans and red and white shoes.
In Ape: Escape: Million Monkeys and Saru Get You ~On Air~, her outfit is changed again. She now wears a short blue jack, with a white shirt under it, blue jeans and red and white shoes.
In Ape Escape: SaruSaru Big Mission, she is back in her Ape Escape 3 outfit.
Natalie, like her grandfather, is very intelligent. She was able to invent many Gotcha Gadgets, including a Pipo Helment, which was the Lab (when they were shrunken).
She can be very short tempered, once getting angry at Spike when he wasn't able to rescue her as quickly as she wanted, and once at Jimmy when he caused the events of Ape Escape 2 to happen. However, she can be caring, such as when Spike, Jimmy and the Professor was under hypnosis by Specter's hypnotic television.
Her personality in the Freaderator Cartoon is a lot different than her game counterpart. She's a lot more sassy and bratty.
- Her actress in Ape Escape 2, Rachael Lillis, voiced Misty in the 4Kids dub of Pokémon.
|Characters||Casi · Jake · Natalie · Professor · Specter · Spike|
|Gadgets||Dash Hoop · Magic Punch · Monkey Radar · R.C. Car · Sky Flyer · Slingback Shooter · Stun Club · Time Net · Water Net|
| || |
|Prehistoric Era/ The Lost Land||Fossil Field · Primordial Ooze · Molten Lava|
|Cenozoic Era/ Mysterious Age||Thick Jungle · Dark Ruins · Cryptic Relics|
|Dimension/Dimension X||Stadium Attack|
|Primitive Age/Oceana||Crabby beach · Coral Cave · Dexter's Island|
|Ice age/New Freezeland||Snowy Mammoth · Frosty Retreat · Hot Springs|
|Dimension/Dimension X||Gladiator Attack|
|Recent Past/Medieval Mayhem||Sushi Temple · Wabi Sabi Wall · Crumbling Castle|
|Present-Day/Futurama||City Park · Specter's Factory · TV Tower|
|Present-Day 2/Specter Land||Monkey Madness|
|Dimension/Dimension X||Peak Point Matrix|